WebsitePanel
Running Different Versions of Microsoft.NET Framework
To run different .Net Framework versions from your application pool, you shall create a virtual directories and assign the mentioned application pool (virtual directories) as different .Net Framework version.
Step.1. Login to your hosting control panel and Click on 'Web' icon and select Websites from the popup menu.
Step.2. Websites list page appears. Click on the "Website name" link
Step.3. 'Website Properties' page appears. Click on 'Virtual directory' Tab.
Step.4. For these next steps, you must have a directory already created for the folders you want to secure. Click Create Directory
Step.5. Enter the name of the directory you already have into the Directory Name box
Step.6. Click Extensions tab
Step.7. Enable the extensions that you need in the directory (1) and Click Update(2) button